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Target family-based

Mestres J. (2005) Representativity of target families in the Protein Data Bank Impact for family-directed structure-based drug discovery. DrugDiscov. Today 10 1629-1637. http //cgl.imim.es/pdbrff/. [Pg.56]

One of the most extensively studied families of peptide toxins, the conotoxins, is isolated from marine cone snails.140 141 Each snail produces a suite of 100-200 peptides in its venom, which is used for the capture of prey, and given that more than 500 species of cone snails are thought to exist, conotoxins represent an enormous diversity of peptide toxins. They have been classified into families, based on their target receptor specificity, and superfamilies, according to their... [Pg.133]

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Target based

Target family

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