Tandem MS with Linear Quadrupole Ion Traps

Note In contrast to tandem-in-space instruments, tandem-in-time instruments neither support precursor ion nor constant neutral loss scanning. While product ion scans just need a precursor to be isolated prior to its fragmentation, both precursor ion and constant neutral loss scan rely on the simultaneous application of selection plus scanning or double scanning, respectively. Fulfilling two criteria at the same time requires two distinct analyzers at work. 

Mass spectrometers incorporating a linear quadrupole ion trap are highly flexible instruments. As discussed in Chap. 4.5, there are two competing concepts available on the market, one employing a LU with axial ejection as part of a hybrid instrument [115], and another, featuring a pure LIT design with radial ejection [116,117], 

Product Ion Scan PIS) Resolving (Fixed) Fragment Resolving (Scan) 

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