Tandem mass spectrometry sorting

Schneiter, R. Brugger, B. Sandhoff, R. Zellnig, G. Leber, A. Lampl, M. Athenstaedt, K. Hrastnik, C. Eder, S. Daum, G. Paltauf, F. Wieland, F. T. Kohlwein, S. D. Electrospray ionization tandem mass spectrometry (ESI-MS/MS) analysis of the lipid molecular species composition of yeast subcellular membranes reveals acyl chain-based sorting/remodeling of distinct molecular species en route to the plasma membrane. J. Cell Biol. 1999,146,741-754. 

Tandem Mass Spectrometry and Sorting (Pocket Change)... 

Figure 32F-2 A tandem mass spectrometry system. The ions produced in the source are filtered in the first quadrupole so that only a selected ion passes through to the collision cell. A collision gas in this cell causes fragmentation of the selected ion. The fragment masses are sorted by the quadrupole mass analyzer and detected. Usually, the collision cell is also a quadmpole operated in such a way that the fragment ions are directed into the mass analyzer.

Electrospray ionization mass spectrometry (ESI—MS is a tandem technique it employs an electrospray ionization device (ESI) to produce bare ions in the gas phase from a supplied (usually aqueous) solution, and supplies these ions as a very dilute gaseous stream to the high vacuum chamber of a mass spectrometer, which is the analyser. This analyser sorts and detects ions by mass/charge ratio (mlz), as cations or as anions, and will report either on request. For coordination complexes, the ESI process can be sufficiently soft ... 

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