T-Stat

Dibucaine (Nupercainal) Doxepin, Topical (Zonalon, Prudoxin) Econazole (Spectazole) Efalizumab (Raptiva) Erythromycin, Topical (A/T/S, Eryderm, Erycette, T-Stat) Erythromycin Benzoyl Peroxide (Benzamycin) Finasteride (Propecia) Fluorouracil, Topical [5-FU] (Efudex) Gentamicin, Topical (Garamycin, G-Mycitin)... 

Brand Name(s) (A/T/S, Akne-Mycin, EES, Emgel, E-Mycin, Eryc, Erycette, EryDerm, Erygel, Erymax, EryPed, Ery-Tab, Erythra-Derm, Erythrocin, PCE Dispertab, Romycin, Roymicin, Staticin, Theramycin, Theramycin Z, T-Stat)... 

Topical Solution 1.5% (Staticin), 2% (A/T/S, Erymax, EryDerm, Erythra-Derm, Romy-cin, TheramycinZ, T-Stat). 

HI Now we use a built-in routine in Excel for the paired t test to see if the two methods in Problem 4-14 produce significantly different results. Enter the data for Methods 1 and 2 into two columns of a spreadsheet. Under the TOOLS menu, select DATA ANALYSIS. If DATA ANALYSIS does not appear, select ADD-INS. Select ANALYSIS TOOLPACK, click OK, and DATA ANALYSIS will be loaded into the tools menu. In the DATA ANALYSIS window, select t-Test Paired Two Sample for Means. Follow the instructions of Section 4-5 and the routine will print out a variety of information including tcafcu ated (which is labeled t Stat) and ftable (which is labeled t Critical two-tail). You should reproduce the results of Problem 4-14. 

T-Stat (Westwood-Squibb) Theramycin Z (Medicis) generic and combination preparations... 

Figure 10-1 The t-STAT system showing a cartridge and the microchip-based electrode assembly. (Reproduced by permission of i-STAT Corporation, East Windsor, NJ.)...

When you click on OK, the computer carries out the procedure and puts the output on the screen. A number of statistical parameters are exhibited. You can find the value of correlation coefficient and its square (in the R Square cell). At the bottom of the output are the parameters of the fit. There are columns labeled Coefficient, Standard Error, t Stat, P-Value, Lower 95%, and Upper 95%. There are two rows for the intercept and slope. The intercept row is labeled Intercept, and the slope row is labeled X Variable. The Coefficient column contains the parameter. The Standard Error column contains the error based on the standard deviation (about 68% confidence). The Lower 95% column contains the parameter decremented by the expected error at the 95% confidence level, and the Upper 95% column contains the parameter incremented by the expected error. To obtain the expected error, you will have to do a subtraction. You should look at the list of residuals to see it there is a systematic curvature in the data, which shows up with residuals having one sign at the ends of the fit and the other sign in the middle. 

GenelD LogFC t-stat raw.p.value Bonf. adj.p BH.adj.p. value By.adj.p. value w- stat raw.p. value Bonf. adj.p... 

National Center for Biotechnology Information (NCBI) http //WWW. ncbi. nlm.nih. gov/geo/info/prin t stats. cgi Stanford Microarray Data Base, http //genome-www5.stanford.edu/... 

---