Systemic lupus erthematosus

The anti-DNA antibody has been used as a marker molecule of Systemic Lupus Erthematosus (SLE) which is a severe autoimmune disease. Enzyme immunoassay is the most reliable, widely used method of assay however, the electrochemical detection method reported here should be interesting for the purpose of a rapid and convenient diagnostic tool of SLE. 

H37. Huang, Y.-P., Miescher, P. A., and Zubler, R. H. The interleukin-2 defect in vitro in systemic lupus erthematosus is reversible in rested cultured T cells. / Immunol. 137, 2545-2548 (1986). H38. Hume, D. A., and Denkins, Y. M. Activation of macrophages to express cytocidal activity correltes with inhibition of their responsiveness to macrophage colony-stimulating factor (CSF-1) Involvement of a pertussis toxin-sensitive reaction. Immunol. Cell. Biol. 67, 243-249... 

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See also in sourсe #XX -- [ ]

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