Synthesisof

Volume 33 Synthesisof High-silica Aluminosilicate Zeolites edited by P.A. Jacobs and J.A. Martens... 

Synthesis of Seco Acid 4 and Completion of the Total Synthesisof Cytovaricin... 

WATTSP.tyiLEsG.TlASWELlX.J., Pombo-ViliarB., Solutionphase synthesisof fTpeptidesusingmicroreactors, Tetrahedron 58,27 ( 2002)5427-5439. 

M. J. KamletandW.H. Gilligan, Synthesisof Mercuric5-Nitrotetrazole , ASWC/WOZ/TR-Zd-J d, AD-A036086 (1976), Naval Surface Weapons Centre, White Oak, Maryland. 

A number of cycloalkyl-, vinyl-, aryl-, and benzyllithium compounds (predominantly benzyl-lithiums) are converted into fluoro derivatives in good to excellent yields, e.g. formation of 4, 5, and 6 19 however, when this method was applied to the synthesisof 3-fluorobenzocyclobutene from the lithium salt a violent explosion occurred when the reaction mixture was warmed from — 70 C to room temperature.20 Various fluoro-substituted thiophenes 7 are obtained when the starting compounds (thiophene, 2-methylthiophene, etc.) arc transformed with al-kyllithium compounds to the corresponding lithium derivatives then fluorinated with perchloryl fluoride at 0 C.21 Potassium tricyanomethanidc is converted at —15 C in triglyme into tricyanofluoromethane in 81 % yield.22... 

The synthesisof compd VI, already mentioned, was described earlier by Stoll Scher-rer (Ref 2) and Dilthey et al (Ref 4). The synthesis of Cyclohexanone Monoperoxide,... 

Wakamatsu K, Kigoshi H, Niiyama K, Niwa H, Yamada K (1984) Stereocontrolled Total Synthesisof (-l-)-Tutin, AToxic Sesquiterpene of Picrotoxane-Type. Tetrahedron Lett 25 3873 Krische MJ, Trost BM (1998) Transformation of the Picrotoxanes The Synthesis of Corianin and Structural Analogs from Picrotoxinin. Tetrahedron 54 7109... 

A variation of this method that removes the water produced in the pyrrole/aldehyde or hydrated aldehyde condensation has been used to produce meso-tetrakis(perfluoroalkyl)porphyrins. Lindsey s laboratory has also reported a rational synthesis of weyo-substituted porphyrins bearing one nitrogen heterocyclic group that can readily be used for preparing other mono-functionalized porphyrins, methods for minimi zing scrambling in the synthesisof tran -porphyrins from dipyrromethanes and aldehydes, and a rational synthesis of porphyrins bearing up to four different meso substituents. ... 

Taub, D., Zelawski, Z.S., and Wendler, N.L., A stereoselective total synthesisof 7a-hydroxy-5,ll-diketotetranorprostane-L16-dioic acid, the major human urinary metabolite of PGE, and PGEj, Tetrahedron Lett., 3667, 1975. 

Volume 33 Synthesisof High-silica Aluminosilicate Zeolites... 

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