Synthesis SYNLIB

The next step is to find all reactions in the other ORAC databases that correspond to a CASP synthesis proposal or to a CASP transform in general. For this purpose CASP can deliver the reactant and product substructures with corresponding differences and put them into a query file for ORAC to search. The detected cross references can be stored in the CASP transform library for quick retrieval. Doing this manually so far for our ongoing transform work we found that many transforms have no corresponding ORAC (or SYNLIB) reactions. It seems that some classical chemistry is not yet represented therein. 

SYNLIB, see Software appendix) and a combination of synthesis-planning software with literature reaction retrieval software is a powerful tool for synthetic chemistry. 

FIZ Chemie = Fachinformation.szentrum Cheniie ISl = institute for Scientific Information IRDAS = ISIS reaction database access system ISIS = integrated scientific information system JSM = Journal of Synthetic Methods MACCS = molecule access system MOS = Metlwd.s in Organic Synthesis, ORAC = Organic Reaction Acce.ss by Computer REACCS = Reaction Access System SMD = standard molecular data SPORE = Solid Phase Organic Reactions, STN = Scientific and Technical Information Network SYNLIB = Synthesis Library. 

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