Synthesis problems multiple answers

This problem illustrates an important point—that there are three perfectly correct answers to this problem. In fact, synthesis problems will rarely have only one solution. More often, synthesis problems will have multiple correct solutions. 

Most synthesis problems will have multiple correct answers. Do not feel that you have to find the "one" correct answer. 

As you work through the following problems, keep in mind that there is rarely only one answer to a synthesis problem. As we leam more and more reactions, you will find that there are often multiple correct ways to achieve a transformation. Don t get stuck into thinking that you have to find THE answer. You may even come across a perfectly acceptable answer that no one else in the class thought of Those are the most exciting moments. There actually is room for you to express some creativity when you solve synthesis problems. Now let s get some practice ... 

Let s start with a question. Can the Wicha strategy be successfully applied to the juvabiones I am not aware that anyone has tried, but I suspect the answer is no . 1 will leave it for you to explain why not (or why yes if you disagree with me). The point I want to make here is that no one solution to a given problem will work for all variations of that problem. Thus there is usually a need for multiple solutions to a given problem (in this case a synthesis problem). I hope this study of a set of approaches (in some cases solutions) to the same problem is educational. 

This alternate answer illustrates a very important point. With synthesis problems, there are often multiple acceptable answers. 

Growing membrane systems have been used to obtain artificial infrabiological systems. Walde et al. [47] have carried out the synthesis of polyadenylic acid in self-reproducing vesicles [48], in which the enzyme polynucleotide phosphorylase carried out the synthesis of poly-A, and membrane vesicle multiplication was due to the hydrolysis of externally provided oleic anhydride to oleic acid. The snag is that the enzyme component is not auto-catalytic. Enzymatic RNA replication in vesicles [49] suffers from the same problem. It is also not known whether redistribution of the entrapped enzymes into newly formed vesicles occurs or not. An affirmative answer would be evidence for vesicle reproduction by fission. 

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