Synthesis of Macrosphelides A and

Sharma and Mouli [111] reported a carbohydrate-based approach for the synthesis of macrosphelides A 178 and E 179 from alcohol 195 and acids 199/199a. Diol 

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Sunazaka T, Hirose T, Harigaya Y, Takamatsu S, Hayashi M, Komiyama K, Omura S. Relative and absolute stereochemistries and total synthesis of (+)-macrosphelides A and B, potent, orally bioavailable inhibitors of cell-cell adhesion. J. Am. Chem. Soc. 1997 19 10247 10248. 

Sharma, G.V.M. and Mouli, C.C. (2002) The total synthesis of macrosphelides A and E from carbohydrate precursors. Tetrahedron Lett., 43, 9159-9161. 

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