Synthesis of 2,5-Dideoxy-2,5-Iminoalditols

SCHEME 13.16 Examples of chemoenzymatic syntheses of 2,5-dideoxy-2,5-iminoalditols based on RAMA-catalyzed aldol reactions. 

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J. Di, B. Rajanikanth, and W. A. Szarek, Fluorinated l,5-dideoxy-l,5-iminoalditols Synthesis of l,5,6-trideoxy-6-fluoro-l,5-imino-D-glucitol (l,6-dideoxy-6-fluoronojirimycin) and 1,4,5-trideoxy-4-fluoro-l,5-imino-D-ribitol (l,2,5-trideoxy-2-fluoro-l,5-imino-L-ribitol), J. Chem. Soc., Perkin Trans. 1 (1992)2151-2152. 

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