Synthesis of an End-Functionalized Block Copolymer Possessing a PEG Segment

SYNTHESIS OF AN END-FUNCTIONALIZED BLOCK COPOLYMER POSSESSING A PEG SEGMENT 

2 Acetal-PEG-Poly(2-yy,N-dimethylaminoethyl Methacrylate) Block Copolymer (46) 

Recently, we have found that a methacrylic ester possessing an amino group at the jS-position of the ester moiety can be 

Linear-poly(ethylenimine) (L-PEI) has often been used for gene delivery as DNA/L-PEI complexes due to its high 

8 ppm were also observed, indicating that the acetal-PEG/L-PEI was successfully synthesized. PIC micelles composed of the obtained acetal-PEG/L-PEI block copolymer and DNA may also have a potential utility as a targetable nonviral gene vector. 

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