Syndromes fetal tobacco syndrome

Habek, D., Habek, J. C., Ivanisevic, M., Djelmis, J. (2002). Fetal tobacco syndrome and perinatal outcome. Fetal Diagn. Ther. 17 367—371. 

In animals, THC crosses the placenta and is excreted in breast milk. There is conflicting evidence concerning teratogenicity in animals, but no definitive evidence in man. However, there have been many anecdotal reports of abnormalities. Although these were without consistent characteristics, the descriptions would readily fit the fetal alcohol syndrome (133-136) and clinical evaluation of the use of cannabis during pregnancy is complicated by the frequent concomitant use of alcohol and tobacco. 

Very many chemicals are recognized teratogens in animals a significantly smaller subset of these is known or suspected to be developmental neurotoxicants in humans. Some of the more significant of the latter group include ethanol, which causes a constellation of effects ranging from fetal alcohol syndrome to alcohol-related neurodevelopmental disorder maternal smoking of tobacco (fetal tobacco syndrome) excess vitamins A and D heavy metals, particularly... 

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