Synartetic acceleration

The direct interaction of the reaction center of a molecular entity with a lone pair of electrons of an atom within that same molecular entity that is not associated with the reaction center or, interaction of the reaction center with the reaction center nor conjugated with the reaction center. Rate acceleration by such a process is referred to as anchimeric assistance. See Intramolecular Catalysis Synartetic Acceleration. 

NEIGHBORING GROUP MEGHANISM ANCHIMERIC ASSISTANCE NEIGHBORING-GROUP PARTIGIPATION INTRAMOLECULAR CATALYSIS SYNARTETIC ACCELERATION N-END RULE... 

PHYSICAL ORGANIC CHEMISTRY NOMENCLATURE Synartetic acceleration,... 

An important difference between the theories behind Figs. 1 and 2 is that one expects from the former that the solvolysis of camphene hydrochloride (12) would be accelerated because it should lead to a synartetic ion (enter and leave from the right-hand side of Fig. 1), whereas it would not be accelerated if the latter theory is correct. Ethanolysis of camphene hydrochloride (12) occurs about 6000 times faster than that of r-butyl chloride but only 2.5 times faster than that of 1,2,2,5,5-pentamethyl cyclopentyl chloride (13). Hence the decision as to whether the ethanolysis of (4) is accelerated depends on which model reaction is chosen for the nonassisted... 

---