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Synaptic association with dysbindin

Dysbdindin-1 may also affect synaptic vesicle fusion via interaction with its known or candidate binding partners sec8, snapin, and syntabulin. Sec8, like dysbindin-1 A and -IB, is associated with presynaptic membranes (Hsu et al., 1996 Vik-mo et al., 2003). It is a member of the exocyst complex... [Pg.197]

As noted earlier (see O Section 2.2.63.i), dysbindin-lB in human synapses is almost exclusively associated with synaptic vesicles. Consequently, our recent finding that dysbindin-lB is reduced in the hippocampal formation of schizophrenia cases confirms our previous quantitative immunohistochemi-cal finding that reduced dysbindin-1 occurs in glutamatergic presynaptic fields of associational and... [Pg.211]


See other pages where Synaptic association with dysbindin is mentioned: [Pg.109]    [Pg.124]    [Pg.141]    [Pg.141]    [Pg.166]    [Pg.175]    [Pg.195]    [Pg.198]    [Pg.140]    [Pg.172]    [Pg.175]   
See also in sourсe #XX -- [ Pg.175 , Pg.211 ]




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