Surfactant properties growth

Past efforts to target a specific deposition site were based on the control of particle size at inhalation. Also, efforts to control growth of particles by adding substances with surfactant properties have been reported. Addition of lauric and capric acids to disodium fluorescein markedly reduces particle growth [22], as does the addition of a cetyl alcohol monolayer to saline droplets [23], Such a reduction of growth would be expected to facilitate particle penetration to more... 

The bacteria apparently produce some kind of diffusible substance. Extracts from bacterial cultures were fractionated and a compound highly effective in inhibiting fungal growth was isolated. The pure compound was active on its own and it was shown to be a new substance, viscosinamide. The compound is a cyclic peptide Fig 5.2 with a lipid tail and has strong surfactant properties (amphiphatic molecule). The compound is similar to other compounds that have been shown to create holes in membranes. 

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