Target surface

Ciruela, F., Soloviev, M. M., Chan, W. Y and Mcllhenney, R. A. (2000) Homcr- Ic/Vcsl-1L modulates the cell surface targeting of group I metabotropic glutamate receptor type la evidence for an anchoring function. Mol. Cell. Neurosci. 15, 36-50. 

R. McMillan, et al. Bistatic Surveillance of Surface Targets - Concept Analysis, 42th Annual Tri-Service Radar Symposium Record, June 1996. 

Q. Zhu, P. von Dippe, W. Xing, D. Levy, Membrane Topology and Cell Surface Targeting of Microsomal Epoxide Hydrolase. Evidence for Multiple Topological Orientations , J. Biol. Chem. 1999, 274, 27898 - 27904. 

Another method for assaying the activity and stereoselectivity of enzymes at in vitro concentrations is based on surface-enhanced resonance Raman scattering (SERRS) using silver nanoparticles (116). Turnover of a substrate leads to the release of a surface targeting dye, which is detected by SERRS. In a model study, lipase-catalyzed kinetic resolution of a dye-labeled chiral ester was investigated. It is currently unclear how precise the method is when identifying mutants which lead to E values higher than 10. The assay appears to be well suited as a pre-test for activity. 

They are usually loaded with HBX, HBX-1 or TNT (70% of the total wt of the bomb) and provided with a hydrostatic tail fuze that functions at a predetermined depth. A nose fuze that functions with instantaneous action on impact may be used to produce a surface burst, when the bomb is used against a surface target(Refs 7,9 15) (See Fig)... 

If the thin-film or surface target consists of two or more atomic species, the energy distribution function of the backscattered protons shows some structure. The... 

Fig. 3.25. Heat flux histories following an ELM of 1MJ/m2 with a power flux triangular waveform (curve 1) with ramp-up and ramp-down phases lasting 300 ds each on a 10mm thick W target under an inter-ELM power flux of 10MWm 2. Curves. (1) incident heat flux load (2) conducted heat flux into the material (3) heat flux spent in melting of the material (the evaporation and black-body radiation heat fluxes are comparatively small and not shown). Curve (4) shows the surface target temperature and (5) shows the temperature of the melt layer. Curve (6) shows the vaporized thickness (amplified of a factor of 1000) and (7) the melt layer assuming that no losses of molten material occur during the ELM [3]...

Gliding Torpedo GT-1. A 2000-lb aerial torpedo developed by the US Navy during WWII. It was released from a plane at a distance up to. 25 miles from a surface target (such as ships concentrated in a harbor or in a convoy)... 

Fig. 13 Computational model for U-Profile die design (A) preland, die land, and free surface as computational domain (B) finite element mesh (symmetry exploited to reduce computational requirements) (C) boundary conditions for simulation of polymer fiow through die and extrudate free surface and (D) relevant profiles (1) preland inlet (2) die land (uniform along flow length) (3) final free surface (target extrudate profile) and (4) symmetry plane.

As with other sectors of our society, the operating environment of the pipeline industry has been profoundly altered by September 11, 2001. Security has been elevated to a priority that previously had not been required when the major threat was an occasional and usually minor act of vandalism. In most cases, the threat with gas pipelines may be economic disruption more than public or environmental safety for most incident locations. The lines are buried through most of their runs and there may be more attractive surface targets. However, the threat is real and is being addressed. It is beyond the scope of this entry to elaborate in detail, but enhanced security measures are being evaluated and implemented throughout the industry. 

Nauman, D. A., Bertozzi, C. R. (2001). Kinetic parameters for small-molecule drug delivery by covalent cell surface targeting. Biochim. Biophys. Acta, 1568,147-154. 

The transfer of information between cells and the subsequent cellular integration of multiple information sources that is necessary to maintain cellular homeostasis and tissue viability—under both normal and adverse, disease-related conditions—involves a variety of different external signaling modalities. These include temperature, membrane potential, mechanical distention and stress, alterations in ion (IT /K ) concentrations, and pheromones and oderants, as well as the more traditional classes of neurotransmitters, neuromodulators, and hormones. These physical stimuli and endogenous chemicals elicit their effects through interactions with cell surface targets, usually proteins, that are classified as receptors (Table 10.1). Once receptors are ac-... 

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