Surface-modified membranes INDEX

Surface plasmon resonance (SPR) allows monitoring label-free interactions between biomolecules in real time. In SPR measurements, one of the biomolecules is immobilized on a sensor surface and the other one is transported in solution across the surface. Binding of the second biomolecule will cause an increase in mass and a proportional increase in refractive index that can be monitored. Gold surfaces are the most commonly used ones and they can be modified or functionalized for the specific binding of particular molecules. For example, biotinylated surfaces enable the immobilization of streptavidin-labeled proteins, and surfaces modified with lipophilic groups allow the immobilization of vesicles creating membrane-like structures to study protein association and dissociation with membranes. 

FIGURE 3.3 The average fluxes of the filtration cycle for the initial PES membrane (1) and the composite membranes modified with HEMA (2), AMPS (3), and qDMAEM (4) vs. the time of the membranes exposure to surface water (river Nivka, Kyiv). The DM of the membranes is 500 20 pg/cm. The duration of the filtration cycle is 1 h at an operating pressure of 0.5 bar. The E. coli index of surface water is 3.52 x 10 CFU/1. 

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