Surface-limited relaxation regime

The obtained results have also been conhrmed by studies on water dynamics and water interaction in bovine serum albumin (BSA p) suspension performed on 300% swollen albumin NP by analysis of H NMR relaxation curves and self-diffusion measurements that showed the presence of two well-separated relaxation rates (Bellotti et al. 2010). These rates have been accounted for a surface-limited relaxation regime of water molecules inside albumin NP (60 wt% of the total water content) and a diffusion-limited relaxation of water molecules into the meso-cavities between the packed NP (40 wt% of the total water content). At higher water content, the appearance of slowly relaxing components was assigned to free water molecules external to the NP, supernatant on the top of the sample. Therefore, the non-freezing and freezing water fractions up to Wiot=300%, determined by DSC measurements, may be associated to the water molecules inside and between the packed NP, respectively. While, at higher water content free molecules external to the NP were also present (Bellotti et al. 2010). 

The MGC skipped Regime 1, due to the limited relaxation of its entangled molecules on the lamellar surfaces, rather than the adjacent reentry folding for the SGC. 

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