Supported Prolinamides in Aldol Reactions

In the first approach, prolinamides have been supported on micelleforming species, dendrimers (32a-c), polystyrene (26, 31a-d), poly-vinylidene chloride, phenolic polymers, ionic liquids, silica (28, 29), other inorganic supports (30), ° and polymer-modified small peptides. Supported prolinamide catalysts have also been prepared by acrylic and styrene (27) copolymerisation. 

These immobilised organocataiysts offer some advantages over small organic catalysts, such as recyclability, simple reaction set-up, easy 

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