Supported Dendritic Catalysts for the Asymmetric Addition of Diethylzinc

Supported Dendritic Catalysts for the Asymmetric Addition of Diethylzinc 

The cross-linked dendritic BINOLate p-71 (20mol%) was also used as a supported catalyst in the asymmetric cyanosilylation of pivalaldehyde in CH2CI2. The catalyst was reused several times after separation from the reaction mixture by filtration. In 20 consecutive reactions, the cyanohydrine product was formed in 90% yield. Initially, an increase in enantioselectivity was observed from 72% 

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E.3. Supported Dendritic Catalysts for the Asymmetric Addition of Diethylzinc... 

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