Supercritical energy optimization

Production plants for supercritical fluid extraction of natural substances have now been in operation for several years. Production costs are significantly influenced by the energy requirement. Energy optimization may improve production economy for existing and future extraction plants. Results of optimization calculations were first published by Eggers 1. These calculations are extended here. 

Duan P, Savage PE. Catalytic treatment of crude algal bio-oil in supercritical water optimization studies. Energy Environ Sci 2011 4 1447. 

The enhanced physical properties for supercritically produced salme-terol (e.g., high crystallinity, polymorphic purity, powder uniformity) correlate well with the enhanced dispersion and flow behavior of this powder. However, as shown in some other investigations (12,28), particle size and shape, surface energy, and crystallinity may have to be optimized separately, using all process parameters available, perhaps including a coformulation step. For some compounds with low solubility in water, a compromise must be found between improved bioavailability and physicochemical stability. 

This method is similar to ASE. except that healing power is supplied by microwaves. MASE has been used for the extraction of pesticides from soil supercritical fluid extraction of CM pesticides from soil. Lopez-Avila ei al. (1998) studied the stability of OCs and OPs when extracted from. solid matrixes with microwave energy. 

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