Summary of Inhibition Types

In the preceding chapters, as well as in this chapter, we have encountered a number of different types of inhibitors. The inhibitors have been classified as competitive, uncompetitive, and noncompetitive. Further, the inhibition can be classified as hnear, parabolic, and hyperbolic. Further types of inhibition, which 

In the linear inhibition, the family of straight lines in the double reciprocal plot of i/uo versus fA (at different fixed concentrations of I) will always have a common intersection point. In the hnear inhibition, the replot of Slopei/A and InterceptyFA from the double reciprocal plot, versus /, is a straight line this type of inhibition was described in Chapter 5. 

In the hyperboUc inhibition, the replot of Slope,/a and/or Intereept,/A versus I is a hyperbola. In the paraboUc inhibition, the replot of Slopei/A and/or Intercepti/A versus I will have a shape of a parabola. These types of inhibition are described in Chapter 6. 

Substrate inhibition Rapid-Equilibrium Random bisubstrate BEB (11.6) Fig. 1 Fig. 2 

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