Summary chromatography report

Since the natural target of macrocyclic antibiotics is the A-acyl-D-alanyl-D-alanine terminus (see Section 2.1), the early choice of suitable substrates for this kind of CSPs was that of amino acids [45]. However, it turned out that the macrocyclic CSPs were very successful not only in amino acids enantioresolution, but also in the separation of a wide variety of different structures. The early stages of application of macrocyclic antibiotics have been surveyed in the different fields of chromatography [1,2]. A summary of the different categories of chiral compounds separated by HPLC on glycopeptides containing CSPs is reported in Table 2.3. 

A.2.2. High-performance liquid chromatography A number of HPLC systems which are suitable for the identification and separation of zaleplon have been reported. A summary is represented in Table 8.7. 

Size exclusion chromatography has been extensively used for the study of metal-containing species in various body fluids and tissues. A summary of some applications is given in Table 1. No attempt has been made to produce an exhaustive list, rather the examples have been chosen to illustrate the various procedures and precautions required when studying the distribution of the various chemical species of an element. More examples can be found in the chapters on the individual elements. Most of the application-s reported provide only partial information on the species. For complete characterisation of a given chemical species a wide range of techniques are required, and these may not be available in a single laboratory. Besides the determination of the metal/metalloid con-... 

Because of the vast usage of SEC techniques in rapidly expanding fields related to life science, at present, we show a limited number of applications in some detail, which have been reported during the limited period. In this section, therefore, a summary of the content of papers dealing with SEC which appeared in Journal of Chromatography during 1982-early 1985 is provided. 

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