Sulfur trioxide, reaction with cyanogen chloride

Sulfur trioxide, reaction with cyanogen chloride, 46, 24... 

An analogous product (252 X = Cl) is formed in the reaction of sulfur trioxide with cyanogen chloride (68AG(E)172). Aryl cyanates also condense with sulfur trioxide to give 1,2,3,5-oxathiadiazines analogous to those formed from dialkylcyanamides (67CB3736). 

Reaction of sulfur trioxide with cyanogen chloride at a temperature not exceeding O C results in the formation of CSI and the 1,4,3,5-oxathiadiazine... 

I-Cyanobenzocyclobctene, 48, 53 8-Cyanoethylhydrazine, from acrylonitrile and hydrazine, 48, 8 reaction with sulfuric acid, 48, 8 Cyanogen bromide, 45, 88 Cyahogen chloride, in preparation of chlorosulfonyl isocyanate, 46, 24 reaction with sulfur trioxide, 46, 24 7-Cvanoheptanal, 49, 27, 28... 

Chlorosulfonyl isocyanate6 (CSI) (57) is a very reactive compound which was first prepared from cyanogen chloride (56) and sulfur trioxide (Graf, 1956) (Scheme 31). CSI (57) undergoes [2+2] cycloaddition reactions with various alkenes initial adducts like (58) and (59) may be hydrolysed to the b-lactams (60) and (61). The cycloaddition reaction also occurs with enamines (62) to give products like (63) and (64) (Scheme 32). 

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