Sulfur-Containing Ferrocenyl Ligands

Indeed, the advantages of using ferrocene as a scaffold for chiral 

The first monosubstituted ferrocene derivatives containing chiral amino-sulfide backbones in the side chain were reported by Bonini et These 

A new class of easily accessible 1,2-disubstituted phosphinamidite-thioether ligands derived from Ugi s amine and based on a ferrocene motif has been 

Wilkinson in Comprehensive Coordination Chemistry, 5, Pergamon Press, Oxford, 1987. 

Pfaltz and M. Lautens, in Comprehensive Asymmetric Catalysis, ed. E. N. Jacobsen, A. Pfaltz, H. Yamamoto, Vol. 2, Springer, Berlin, 1999, pp. 833-884. 

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In addition, Bonini et al. have shown that a planar chiral sulfur-containing ferrocenyl-oxazoline carbinol ligand, depicted in Scheme 3.59, could also be used to catalyse the addition of ZnEt2 to benzaldehyde with a moderate enantioselectivity (46% ee). ... 

Scheme 3.59 Sulfur-containing ferrocenyl-oxazoline carbinol ligand for addition of ZnEt2 to benzaldehyde.

Scheme 2.23 Cu-catalysed 1,4-addition of ZnEt2 to ethyl pentylidene malonate with sulfur-containing phenylphosphorus ferrocenyl ligand.

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