Sulfoxidation uncatalyzed

SCHEME 101. Uncatalyzed asymmetric sulfoxidation with chiral hydroperoxides as oxidants... 

Ultra-trace analysis, hydrogen peroxide determination, 638 Ultraviolet see UV Uncatalyzed sulfoxidations, 472-4 Uncertainty, analytical methods, 624 UN Environment Programme (UNEP) chemicals safety, 745, 747 SIDS database, 622 UnfunctionaUzed olefins... 

In combination with H2O2 (salen)Mn(III) complexes 173a, b, i-n have also been employed by Jacobsen and coworkers as catalysts for the asymmetric oxidation of sulfides to sulfoxides, without a need for additives. From the structurally and electronically different Mn-salen catalysts screened, 173i turned out to be the most active and selective one (equation 58)389. While dialkyl sulfides underwent uncatalyzed oxidation with H2O2, aryl alkyl sulfides were oxidized only slowly compared with the catalyzed pathway. Using... 

Because of its insolubility in common aprotic solvents, iodosylbenzene is of limited use for uncatalyzed oxidations in such media. The o-tert-butylsulfonyl derivative 6 of iodosylbenzene, on the other hand, is moderately soluble (0.08 M) in chloroform and has been employed for uncatalyzed oxidations of sulfides and phosphines to sulfoxides and phosphine oxides (Scheme 3) [17]. 

HO", to the enhancement of its activity in aqueous dimethyl sulfoxide as the concentration of water approaches low values.) Wang et al. (2011) demonstrated methylation of phenol and benzene-1,2-diol derivatives with 1,3,5-tiioxane (e.g.. Scheme A) in supercritical water, accelerated compared to the solvent-free reaction. The authors describe the reaction as uncatalyzed, though acid catalysis by water or by hydrogen ion is likely (see Section 3.6.1). 

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