Sulfhydryl groups esterases

Allyl formate is cleaved by nonspecific esterases to allyl alcohol, which is then oxidized by alcohol dehydrogenases to the reactive acrolein, which is responsible for the hepatotoxic action. The toxicity of allyl alcohol via its metabolite acrolein is dependent on the concentration of glutathione (GSH). After depletion of GSH, the reactive metabolite of allyl alcohol can bind to essential sulfhydryl groups in the cellular macromolecules, leading to structural and functional modifications that can be responsible for hepatic injury. Appearance of lipid peroxidation signals events that follow toxication mechanisms initiated by acrolein, and subsequent and continued lipid peroxidation could be merely the consequence of cell death. 

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