Suggestions about Mechanisms of CNS Drug Action

One of the most interesting applications of receptor mapping is to provide new hypotheses about how various drugs produce their physiological effects. It seems that it is only by understanding where drugs act within the complex circuits in the brain that one can fully understand how 

Correlation of CNS Areas with High Opiate Receptor Density and Opiate Effect  

Analgesia (Head) Substantia gelatinosa of spinal trigeminal nucleus 

Alteration of pituitary hormone Infundibulum, posterior lobe of 

Suppression of visceral reflexes Vagus nerve and its nuclei (e.g., nucleus tractus solitarius) 

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