Sugars sensors

Fig. 8.13 Dendritic sugar sensor based on boronic acid/glycol interaction (G2 = 2nd generation according to Shinkai etal.)-For the sake of clarity only two of the eight end groups are shown in the boxed formula...

Egashira et al. have observed ECL from various hydroxyl compounds, which has led to the development of alcohol and sugar sensors [65], ECL is... 

Egashira et al. observed ECL from various hydroxyl compounds this led to the development of alcohol and sugar sensors [73, 74] ECL is observed upon voltagecycling of basic aqueous solutions of various sugars and simple vicinal alcohols between -1-1.4 and —1.2 V (vs. Ag/AgCl). While the mechanism is not clear, the authors state that aldehyde excited states may be formed no spectral data is given as the emission is very weak. 

Figure 6-4 Structures of arylboronic acid-based sugar sensors.

Physical Measurements. - The use of aryl boronic acid derivatives as sugar sensors is referred to in Part 2.4 above. 

Egawa Y, Seki T, Takahashi S et al (2011) Electrochemical and optical sugar sensors based on phenylboronic acid and its derivatives. Mater Sci Eng C 31 1257-1264... 

Boronic acid-based biosensors to detect saccharides The recognition of saccharides, especially o-glucose, is of particular interest, owing to their correlation to diabetes and human cancers. The specific recognition of boronic acid for -diols provides a sensing selectivity. In the sugar sensors based on boronic acids (Figure 8), fluorescent, colorimetric, or electrochemical methods can be used as readout units. 

Figure 4 Bessman-Schultz catalyst-type sugar sensor.

The interactions between boronic acids and diols have been widely applied to the development of sugar sensors, insulin delivery systems, lipase inhibitors, and human immunodelidency virus (HIV) inhibitors. ... 

Other molecular complex-based sugar sensors have been reported, " including those that form complexes in the presence of polycations and those that utilize polymers modifled with boronic acid functional groups,hydrogels, - and nanoparticles. ... 

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