Sugar, incompatibilities with

The classical method for introducing the fluorine atom to the anomeric center is to treat per-O-acetylated sugars with hydrogen fluoride [15], using which a-glycosyl fluorides can be prepared stereoselectively, however, the procedure is incompatible with any acid-sensitive functionalities present in the molecule. In addition, hydrogen fluoride is highly corrosive, which makes this method unattractive to many... 

Constitution XV for sucrose has up to the present satisfied all demands made upon it. Like its precursors, I and II (page 6), it was not incompatible with physical properties of sucrose such as the magnetic rotation, or the parachor, although the latter claim has been denied. Von Lippmann lists a great many early determinations of the physical properties of the sugar more recent measurements include the heat of combustion, the molecular weight in liquid ammonia, and various optical and electrical constants. ... 

A variety of different artificial sweeteners have been approved for use in oral liquid dosage forms by the FDA. One general characteristic for artificial sweeteners is their very high sweetness compare to sucrose. This also results in a much lower concentration needed in the formulation, which can lower the cost and/or risk of incompatibility with the drug or other excipients. Additionally, a sugar-free formulation... 

Isoniazid Isoniazid is incompatible with sugars. Isoniazid overdose may be severe to fatal, and treatment is symptomatic and supportive, including stomach wash for control of convulsions and treating metabolic acidosis. Administration of pyridoxine and hemodialysis may be needed. Isoniazid interacts with carba-mazepine, phenytoin, diazepam, triazolam, chlorzoxazone, theophylline, ethosux-imide, enflurane, cycloserine, and warfarin. 

Cycloaddition reactions between azides and alkynes—exemplified by the Huisgen 1,3-dipolar cycloaddition—have tremendous potential for the development of biomolecules and have been employed for conjugation of sugars to peptides [184]. Drawbacks of the Huisgen cycloadditions, however, are poor regioselectivity and incompatibility with physiological conditions. These limitations, which hinder MOE applications in living cells, were first overcome by cop-... 

Differential scanning calorimetry experiments with some directly compressible tablet excipients suggests that aspartame is incompatible with dibasic calcium phosphate and also with the lubricant magnesium stearate. Reactions between aspartame and sugar alcohols are also known. 

Incompatibilities with other substances, such as bentonite, magnesium trisilicate, talc, tragacanth, " sodium alginate, " essential oils, " sorbitol, and atropine, " have been reported. It also reacts with various sugars and related sugar alcohols. ... 

Incompatible with dilute acids, which cause hydrolysis of sucrose to invert sugar, and with alkaline earth hydroxides, which react with sucrose to form sucrates. 

The ideal chemical probe for the structure of a solvent should bring into play reactants that are less volatile and more soluble in water, this being apparently incompatible with a lipophilic character. The use of a diene linked to a free sugar, according to reaction (11.7), approaches this ideal. A comparison of lines 3 and 4 of Table 11.1 shows that this reaction is also accelerated in pure water and that this is also the consequence of an increase in the entropy activation. Thus, the hydrophobic effect can take place between the diene and dienophile close to the sugar part. 

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