Succinylcholine dichloride

By the etherification of succinic acid chloroanhydride with dimethylaminoethanol hydrochloride in the presence of sodium hydroxide succinylcholine was prepared. Then the obtained succinylcholine was purified. To the succinylcholine the methylchloride was added (1 2 mols) and the succinylcholine dichloride was obtained as white powder. 

Succinylcholine Succinylcholine, 2,2 -[(l,4-dioxo-l,4-butanediyl)fcw(oxy)]few[Af,Af,Af-trimethylethanaminium(diacetylcholine)] dichloride, which can be viewed as a dimeric molecule of acetylcholine (diacetylcholine), is synthesized by reacting succinic acid dichloride with 2-dimethylaminoethanol and subsequent transformation of the resulting bM-(2-dimethy-laminoethyl)succinate (15.1.13) into a quaternary salt, succinylcholine (15.1.14) [20-24]. 

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