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Succinimidyl alkyl ester

PEG succinimidyl alkyl ester MSPA, MSBA PEG acylating amide 40, 41... [Pg.386]

Verdini and coworkers [122] have introduced the 2-methyl-2-(2 -ni-tro)phenoxy-propionyl (Mnp) group for the preparation of stable monopro-tected gem-diamino alkyl residues 27 via IBTFA treatment of the carboxamide precursor 26. The precursor 26 is prepared by coupling amino a-carboxamide and 2-methyl-2-(2 -nitro)phenoxy-propionic acid as its O-succinimidyl ester 25. Hydrochloride salts, such as 27, are generally stable, crystalline compounds that can be stored at room temperature for several months. Once deprotonated, 27 is stable enough for acylation reactions (Scheme 9) [122]. [Pg.662]

See other pages where Succinimidyl alkyl ester is mentioned: [Pg.386]    [Pg.386]    [Pg.46]    [Pg.52]    [Pg.799]    [Pg.40]    [Pg.242]    [Pg.1234]    [Pg.26]    [Pg.196]    [Pg.197]    [Pg.744]   


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Alkyl esters

Esters alkylation

Succinimidyl ester

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