Subtype-selective estrogens

Nuclear Receptors as Drug Targets. Edited by Eckhard Ottow and Hilmar Weinmann Copyright 2008 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim ISBN 978-3-527-31872-8 

---

Veeneman, G.H. (2005) Non-steroidal subtype selective estrogens. Current Medicinal Chemistry, 12, 1077-1136. 

In the forthcoming years many questions will be answered and will give more insight into the full potential of subtype-selective estrogens. Further design of fine-tuned subtype-selective ligands is mandatory and will undoubtedly widen the therapeutic scope of ER modulators. Future evaluation of the different ligand classes in appropriate animal models may uncover additional clinical indications in which subtype-selective ER modulators offer therapeutic benefits. 

---