Substructure minicomputer

Hagadone, T.R. Howe, W.J. Molecular Substructure Searching Minicomputer-Based Query Execution . J. Chem. Inf. Comput. Sci. 1982, 22, 182-186. 

The use of pairs of minicomputers in parallel for the substructure search system of STN International is well-known, and is discussed elsewhere in these proceedings, as is another proposal for a substructure search system based on a multiprocessor architecture. ... 

The atom connection table has been used for many years, mainly for storage and retrieval of chemical structures and substructures. CAS became the first major user of connection tables when the Chemical Registry System was established. It was then followed by Telesystemes-DARC (Description, Acquisition, Retrieval, and Correlation) devised at the University of Paris. In comparison with the CAS format, that used in DARC was definitely more compact and easier to process on minicomputers. 

Figure 7. General hardware-component configuration of substructure-search system. Front end consists of graphics minicomputers. Back end consists of dedicated minicomputer, intelligent disk controller, and dedicated disk.

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