Substitution and condensation reactions

We have intentionally selected example reactions (Figs. 29-33) that would not usually be immediately obvious to a chemist. The examples chosen have all been concerned with rearrangements of various types, since their courses are frequently difficult to predict. It remains to emphasize that the reactivity functions contained in EROS perform perfectly well with other types of reaction. This is true, for example, with reactions that a chemist could derive directly from an analysis of the functional groups in a molecule. Thus, EROS predicts addition reactions to carbonyl compounds, nucleophilic substitutions, and condensation reactions, to name just a few examples. In all these reaction types, the possibility of assigning a quantitative estimate to the reactivity at the various sites via the reactivity functions is of particular merit. It... 

What is in effect a cycloaddition is brought about by combined condensation and substitution reactions when acid hydrazides react with 2-dimethylamino-3-methyl-4-thiobenzodiazepine (90MI1) (Scheme 42). Another method of making a triazolobenzodiazepine, again involving combined substitution and condensation reactions, took place when a 2-thiobenzodiazepine reacted with ethyl carbazate (91JHC365) (Scheme 43). 

You ve already learned about substitution and condensation reactions in Sections 23.1 and 23.3. Two other important types of organic reactions are elimination and addition. 

The decrease of intensity of absorptions caharacteristic to the hydroxylic groups and aromatic rings can be correlated with the participations of structural units of lignins in substitutions and condensation reactions and the creation of conditions for obtaining nanoparticles. 

C. L. Recksiedler, B. A. Deore, M. S. Freund, Substitution and condensation reactions with poly(anilineboronic acid) reactivity and characterization of thin films, Langmuir 2005, 21, 3670. 

CHAPTER 17 CARBONYL ALPHA-SUBSTITUTION AND CONDENSATION REACTIONS... 

Besides substitution and condensation reactions, there also are several other important types of organic reactions. In an elimination... 

Substitution and condensation reactions of a series of benzo- and dibenzo-thiopyran dioxides have been studied. Methylation of compounds... 

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