SUBJECTS depolarisation

There is now increasing evidence that cannabinoid receptors involved in the inhibition of neuroeffector transmission are subject to an endogenous tone (Table 5). A typical example is the presynaptic CB, receptors on GABAergic neurons synaps-ing with the pyramidal neurons in the rat hippocampus (Wilson and Nicoll 2001). Depolarisation of the latter neurons causes an increase in formation of endo-... 

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