Subject biochemical engineering

Biochemical engineering is a multidisciplinary subject which covers many fields. Efforts to make the industrial operation of a biological process effective and economically viable involves substantial interaction between microbiologists, bio-... 

The process we wish to consider is one in which a primary chemical species is modified by reaction with a number of secondary species Aat,. . . Ai in succession. These secondary species have to be prepared specially for the appropriate stage of the process and must be available at the right time otherwise the whole process is rendered valueless. Such unstable preparations are not uncommon in biochemical engineering. If the preparation of A , n = 1,. .. A, is subject to random failure, the preparation of more than one batch of it will increase the probability of its being available at the right time. However, this must be carefully balanced against the increased cost of these extra preparations and a problem of optimal specification arises. The system is illustrated in Fig. 8.1 r denotes the number of batches of A that are prepared. 

Because of the broad nature of this subject, this chapter addre. ses only intnxiuc-tory matter as it applies to biochemical engineering. The reader is refened to three excellent references in the literature for an extensive and comprehensive treatment of this new discipline. ... 

Fig. 14.2 Nanobiocatalysis publications by subject area (1995-2009). Physics (combined) physics, apphed physics, condensed matter, Materials science (combined) materials science, multidisciplinary materials science, biomateiials, Biochemistry (combined) biochemistry molecular biology biochemical research methods, Medicine pharmacology (combined) pharmacology pharmacy engineering, biomedical medicine, research experimental chemistry, medicinal...

Web addresses that are useful for biochemical research are presented in Tables El.l and E1.2. Many of the current Web sites you will need are listed here however, what about new Web sites that have been established since publication of this book Millions of new Web sites are created every year. To access these new sites, you need the help of a search engine, a searchable directory that organizes Web pages by subject classification. Major search engines include AltaVista, Excite, HotBot, Lycos, Netscape Search, and Yahoo As you surf the Web, you may find sites you wish to save and review at a later date. You may use the bookmark (Netscape) or favorite (Explorer) function to save it for the future. 

In mathematical system theory, the subject of model reduction has been studied for about 30 years. The focus is on model reduction of linear systems, in particular methods based on singular value decomposition. One of the best known of these methods is balanced truncation. It is used extensively for various engineering purposes, such as electronic chip design and the reduction of models of aerospace structures. This method does not require the type of a priori information about the system mentioned above. Only recently has it been tried out on biochemical systems [105, 106]. 

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