Subcomponent self-assembly

Mai, P Schultz, D. Beyeh, K. Rissanen, K. Nitschke, J. R. An unlockable-relockable iron cage by subcomponent self-assembly. Angew. Chem. Int. Ed. 2008, 47, 8297-8301. 

Construction, Substitution, and Sorting of Metallo-Organic Structures via Subcomponent Self-Assembly... 

Nitschke, J. R. Constraction, substimtion, and sorting of metaUo-organic structures via subcomponent self-assembly. Acc. Chem. Res. 2007, 40, 103-112. 

Subcomponent Self-Assembly as a Route to New Structures and Materials... 

Over the course of the past four years, we have developed and employed the technique of subcomponent self-assembly toward the creation of increasingly complex structures. This technique, itself a subset of metallo-organic self-assembly [11-13],... 

In our own laboratories, initial proof-of-concept experiments established the utility of subcomponent self-assembly based upon copper(I) coordination and imine bond formation, most usefully in aqueous solution [24]. We have subsequently developed our research program along three main lines, seeking responses to a series of questions. 

Our first line of research asks how simple subcomponents might be used to create complex structures via self-assembly. How may self-assembly information be encoded into the subcomponents What other means of encoding self-assembly information into the system might be employed, such as solvent effects and pH Are there structures that are readily accessible using subcomponent self-assembly that are difficult or impossible to create otherwise How may this method be used to generate topological complexity ... 

The first study we undertook [24] validated the use of subcomponent self-assembly using aqueous copper(I), as well as taking initial steps in the directions of construction, sorting, and reconfiguration. 

Figure 1.2 Intersection of dynamic covalent and supramolecular spaces during subcomponent self-assembly.

Many of the complexes prepared through subcomponent self-assembly underwent clean substitution chemistry, which may operate both at covalent and coordinative levels. As discussed below, driving forces for such substitutions included the relief of steric encumbrance, the substitution of an electron-poor subcomponent for an electron-rich one, the use of pK i differentials, and the chelate effect. 

The mechanical bond (catenanes, knots, and rotaxanes) 12TCC(323)19. Metal—organic container molecules through subcomponent self-assembly, particularly, iron(ll) salts—pyridine derivatives 13CC2476. 

J. R. Nitschke, Chem. Eur. J. 2008,14,4585-4593. An imino-boronate construction set for subcomponent self-assembly, (c) E. Sheepwash, V. Krampl, R. ScopeUiti, O. Sereda, A. Neels,... 

Mosquera J, Zarra S, Nitschke JR (2014) Aqueous anion receptors through reduction of subcomponent self-assembled structures. Angew Chem Int Ed 53(6) 1556-1559... 

Bilbeisi RA, Clegg JK, Elgrishi N, de Hatten X, Devillard M, Breiner B, Mai P, Nitschke JR (2011) Subcomponent self-assembly and guest-binding properties of face-capped Ee4L4 capsules. J Am Chem Soc 134 5110-5119... 

Ronson TK, Zarra S, Black SP, Nitschke JR (2013) Metal-organic container molecules through subcomponent self-assembly. Chem Commun 49 2476... 

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