Stylomecon

Stylomecon heterophylla (Benth.) AUocryptopine, berberine, chelerythrine, coptisine, cryptopine. 465 b-d... 

From the plant Stylomecon heterophylla, a new alkaloid stylophylline was isolated. Since it is the enantiomer of the already known (— )-)3-hydrastine, it represents (— )-a-hydrastine. Recently, the isolation of (— )-bicuculline from Corydalis severtzovii was reported. The elucidation of the relative and absolute configuration of phthalideisoquinoline alkaloids was independently and simultaneously achieved by several groups of workers (60, 78, 79, 365-368, 419, 540). Although different methods were applied [model compounds, IR, and NMR spectroscopy, pAgo mcs optical rotation, preparation of corresponding diols (type II), 1-benzyl-tetrahydroisoquinoline (VII), and tetrahydroprotoberberine compounds... 

B-hydrastine isoqmnoltne Corydalis limbiillifera(Fumariaceae), Stylomecon heteiophylla (Papaveraceae), Berberis laurinn, Hydraslis canadensis Berberidaceae) competitive GABA antagonist [180]... 

Stylomecon heterophylla (Benth) 0. Tayi, Styhphorum diphyllum (Michx.) Nutt. 

Stylomecon heterophylla (Benth.) G. Tayl. (syn. Meconopsis heterophylla Benth.), indigenous to North America, contains small quantities of alkaloids (Tables XL and XLI). Its major alkaloid is cryptopine (311) together with allocryptopine (310), protopine (309) and (-)-a-hydrastine (331) (140). 

Stylomecon heterophylla (Benth.) G. Tayl. (syn. Meconopsis heterophylla)... 

Allocryptopine C2,H2,N05 369.42 160-161 (a-form) and 169-171 (/8-form) Dactylicapnos macrocapnos, Argemone bocconia, Eschscholl zia. Glaucium, Macleaya, Meconopsis, Papaver. Sanguinaria. Stylomecon. Chelidonium, Thalictrum species 485-91-6 (a-form) and 24240-04-8 (/8-foim)... 

Cryptopine C 2 H23N05 369.42 221-223 Corydalis. Dicentra. Argemone, Meconopsis. Papaver, Stylomecon, Thalictrum species 482-74-6... 

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