Struma ovarii

Toxic adenoma Thyroid cancer Struma ovarii... 

A low RAIU indicates the excess thyroid hormone is not a consequence of thyroid gland hyperfunction. This may be seen in painful subacute thyroiditis, painless thyroiditis, struma ovarii, follicular cancer, and factitious ingestion of exogenous thyroid hormone. 

J. Ectopic thyroid tissue (struma ovarii, thyroid carcinoma metastases)... 

Dardik RB, Dardik M, Westra W, Montz FJ. Malignant struma ovarii Two case reports and a review of the literature. Gynecol Oncol 1999 73 447-451. 

FIGURE 18.45 Struma ovarii is a form of monodermai teratoma in which thyroid tissue predominates. The thyroid ceiis show strong nuciear staining for thyroid transcription factor 1 (TTF-1), as shown here. The tumor ceii cytopiasm and the coiioid aiso stain positiveiy for thyrogiobuiin. 

There is a greater role for immunohistochemistry in the diagnosis of monodermai teratomas. Some examples of struma ovarii are largely cystic and contain few follicles grow in unusual patterns or are composed of cells with clear or eosinophilic cytoplasm ... 

Szyfelbein WM, Young RH, Scully RE. Cystic struma ovarii A frequently unrecognized tumor A report of 20 cases. Am J Surg Pathol. 1994 18 785-788. 

Devaney K, Snyder R, Norris HJ, et al. Proliferative and histologically malignant struma ovarii A clinicopathologic study of 54 cases. Int J Gynecol Pathol. 1993 12 333-343. 

Thyroid hormones are typically produced in struma ovarii and struma carcinoids of the ovary in subclinical levels. Hyperthyreosis seems to be present in only 25%, and thyrotoxicosis occurs in only 5% of patients with struma ovarii (Fig. 9.13) [37]. Primary... 

Fig. 9.13. Struma ovarii. Transaxial CT in a young woman who presented with a complex adnexal mass at sonography and no evidence of hyperthyreosis. A left adnexal (arrow) surrounded by ascites is demonstrated in the cul-de-sac. It is well defined, shows a thin wall, and demonstrates a solid and cystic architecture. Within the lesion a locule (asterisk) of high density presents hemorrhage. By bladder. Courtesy of Dr. T.M. Cunha, Lisbon...

Teratomas are the most common ovarian neoplasm in women under 45 years of age, and account for up to 70% of tumors in females less than 19 years of age [67]. Ovarian teratomas derive from germ cells and are classified into three main categories, among vdiich the mature cystic teratomas account for 99%. Less common types of mature teratomas are the monodermal teratomas, which include the struma ovarii and carcinoid tumors. It is typical for monodermal teratomas not to be cystic but contain... 

Monodermal teratomas are composed predominantly or solely of one tissue type. They include struma ovarii, ovarian carcinoid tumors, and tumors with neural differentiation. 

Struma ovarii is the most common type, and accounts for 3% of all mature teratomas. It consists predominantly or solely of mature thyroid tissue. A mixed morphology with acini filled with thyroid colloid, hemorrhage, fibrosis, and necrosis is found. Rarely struma ovarii may produce thyrotoxicosis. 

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