Structure-antioxidant activity

GUO Q, ZHAO B, SHEW s, Hou J, HU J and xiN w (1999) ESR study of the structure -antioxidant activity relationship of tea catechins and their epimers, Biochem Biophys Acta, 1427, 13-23. 

RICE-EVANS c A, MILLER N J and PAGANGA G (1996) Structure-antioxidant activity relationships of flavonoids and phenolic acids, Free Rad Biol Med, 20, 933-56. 

Di Majo D, Giammanco M, La Guardia M, Tripoli E, Giammanco S and Finotti E. 2005. Flavanones in citrus fruit structure-antioxidant activity relationships. Food Res Int 38(10) 1161-1166. 

Silva MM, Santos MR, Caroco G, Rocha R, Justino G, Mira L. 2002. Structure-antioxidant activity relationships of flavonoids A re-examination. Free Radic Res 36 1219-1227. 

Justino GC, Santos MR, Canario S, Borges C, Florencio MH, Mira L. 2004. Plasma quercetin metabolites Structure-antioxidant activity relationships. Arch Biochem Biophys 432 109-121. 

R17. Rice-Evans, C. A., Miller, N. J., and Paganga, G., Structure-antioxidant activity relationships... 

Investigation of replacement of the 5-methoxy group by substituents with different electronic and lipophilic properties and methylation of the indole nitrogen or its replacement by a sulfur atom was evidence for the shift of the 5-methoxy group to the 4-position of the indole nucleus led to the most active radical scavenger but much less effective as a cytoprotectant [135]. 5-alkoxy-2-(N-acylaminoethyl)indole (Fig. 15) appeared as the key feature to confer both antioxidant and cytoprotective activity to the structure. Antioxidant activity seems essential for cytoprotection, but it is not sufficient, and there is no statistically significant correlation between the two types of activity. 

Ribeiro, I.A. Ribeiro, M.H.L. 2008. Naringin and naringenin determination and control in grapefruit juice by a validated HPLC method. Food Control 19 432-438. Rice-Evans, C.A. Miller, N.J. Paganga, G. 1996. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic. Biol. Med. 20 933-956. Rietjens, I.M.C.M. Boersma, M.G. Haan, L.D. Spenkelink, B. Awad, H.M. Cnubhen, N.H.P. van Zanden, J.J. Woude, H.V.D. Alink, G.M. Koeman, J.H. 

Farkas, O. Jakus, J. Heberger, K., Quantitative structure-antioxidant activity relationships of flavonoid compounds, Molecules, 2004, 9, 1079-1088. 

By using the TEAC assay, Rice-Evans et al. established a structure-antioxidant activity relationship of flavonoids [28, 130-134]. The antioxidant activity of a flavonoid is determined by the following structural elements [28, 130-134] ... 

Structure-Antioxidant Activity Relationship in Phenolic Adds.331... 

Rice- Evans, C.A., Miller, N.J. Paganga, G. (1996). Structure-Antioxidant Activity Relationships of Flavonoids and Fenolic Acids. Free Radical Biology and Medicine, Vol 20, pp. 933-956, ISSN 0891-5849. 

Rice-Evans CA, Miller NJ, Paganga G. Structure-antioxidant activity relationships of flavonoids and phenohc acids. Free Radic Biol Med 1996 20 933-956. 

---