Strobilurus tenacellus, strobilurins

By the early 1980s, the in vitro activity of strobilurin A, the compound from Strobilurus tenacellus, and oudemansin A, from Oudemansiella mucida, had been completely characterised13 (Figure 4.23) and the mode of action was known to be the inhibition of electron transfer in complex... 

T. Anke, F. Oberwinkler, W. Steglich and G. Schramm, The Strobilurins-new antifungal antibiotics from the basidiomycete Strobilurus tenacellus, J. Antibiot., 1997, 30, 806-810. 

The cytochrome be, complex of Saccharomyces cerevisiae. A few amino acids (shown in blue) In Strobilurus tenacellus are responsible for Its natural resistance to strobilurins and oudemansins (binding pockets Qo and Qi ochre, b and b haem pink, FeS cluster yellow and brown). 

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