Streptozocin extravasation

Streptozocin—vesicant-avoid extravasation have 50% dextrose available in case of sudden hypoglycemia monitor closely for renal impairment... 

Streptozocin -alkylating agent cell cycle independent -nephrotoxicity—can be dose-limiting -nausea and vomiting—may get progressively worse with continued administration -mucocutaneous effects (mucositis, stomatitis, diarrhea) -bone marrow suppression -irritant if extravasated (not vesicant) -delirium or depression -risk of secondary leukemias... 

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See also in sourсe #XX -- [ ]

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