Streptococcus oralis

T. Fujiwara, T. Hoshino, T. Ooshima, S. Sobue, and S. Hamada, Purification, characterization, and molecular analysis of the gene encoding glucosyltransferase from Streptococcus oralis, Infect. Immun., 68 (2000) 2475-2483. 

Kilian M, Mikkelsen L, Henrichsen J Taxonomic study of viridans streptococci Descriptions of Streptococcus gordonii sp. nov. and emended descriptions of Streptococcus sanguis (White and Niven 1946), Streptococcus oralis (Bridge and Sneath 1982), and Streptococcus mitis (Andrewes and Horder 1906). Int J Syst Bacteriol 1989 39 471 184. 

In combination with chemical synthesis, glucansucrases (GTF-R from Streptococcus oralis and GTF-A from Lactobacillus reuteri) were used to produce thio-glucosides, which are tolerated by most biological systems but are less sensitive to acid/base or enzyme-mediated hydrolysis than G-glucosides [138]. 

B. subtilis, S. lutea, C. albicans P. aeruginosa and R. rubra E. coli, S. aureus, Listeria monocytogenes. Salmonella enteritidis Streptococcus oralis. Streptococcus anginosus. Streptococcus intermedius and Streptococcus sanguis, Enterobacter aerogenes. Micrococcus roseus. 

Immunologic A 64-year-old woman developed persistent fever with mucositis and submandibular phlegm, not responsive to antibiotics. She was on therapy with mesalazine for ulcerative colitis, which was currently in remission, and levothyroxine for hypothyroidism. Laboratory tests showed leukopenia with severe neutropenia, and blood culture positive for multi-resistant Streptococcus oralis. The syndrome was managed with antibiotics and filgrastim. The latter drug yielded a scarce benefit, with a modest neutrophil count recovery, which was lost after its discontinuation. Mesalazine was then discontinued, and the patient had a complete and stable normalisation of her neutrophil count within the following 20 days [86 ]. 

---