Strain-induced alignment in a gel

Ishii Y, Markus MA et al (2001) Controlling residual dipolar couplings in high-resolution NMR of proteins by strain induced alignment in a gel. J Biomol NMR 21(2) 141-151... 

Vader D, Kabla A, Weitz D, Mahadevan L (2009) Strain-induced alignment in collagen gels. 

Solution-derived RDCs are important angular constraints in the structure determination of membrane proteins as well as their solution state counterparts. Strained polyacrylamide gels are able to induce the necessary weak alignment of protein samples embedded in spherical micelles. The incorporation of proteins into the gel matrix is not straightforward, but Jones and Opella have outlined a number of methods for this. Similar methods were used by Howell et al. in their structure determination of the mercury transport... 

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