Strain halides

Burkholderia cepacia strain 2CBS is able to degrade ort/jo-halogenated benzoates by dioxygenation to catechol with the elimination of halide and decarboxylation. The enzyme contains a ferredoxin-and a Rieske-type [2Fe-2S] center. These could be distinguished on the basis of their EPR spectra, and the results were compared with those for other [2Fe-2S] clusters (Riedel et al. 1995). 

Schaefer JK, RS Oremland (1999) Oxidation of methyl halides by the facultative methylotroph strain lMB-1. Appl Environ Microbiol 65 5035-5041. 

A two-component 2-halobenzoate 1,2-dioxygenase has been purified from Pseudomonas cepacia strain 2CBS that is able to metabolize 2-fluorobenzoate, 2-chlorobenzoate, 2-bromobenzoate, and 2-iodobenzoate to catechol by concomitant decarboxylation and loss of halide (Fetzner et al. 1992). The inducible 2-halobenzoate 1,2-dioxygenase consisted of... 

Kaschabek SR, W Reineke (1995) Maleylacetate reductase of Pseudomonas sp. strain B13 specificity of substrate conversion and halide elimination. J Bacterial 177 320-325. 

Reactions with seven- to nine-membered cydic allylic carbonates or halides give the corresponding cydic allyltitanium compounds. These reagents add to aldehydes and imines with moderate to excellent diastereoselectivities [59]. The allyltitanium compound generated from 1-vinylcyclopropyl carbonate reacts regioselectively with aldehydes and ketones at the less substituted carbon atom to provide alkylidenecydopropane derivatives, as shown in Scheme 13.29 [60], The regiochemical outcome of the reaction can be rationalized by assuming an equilibrium between two allyltitanium spedes that favors the less strained tertiary structure. 

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