Storage amplitude modulation

Kett et al. [1.162] studied Tg in freeze-dried formulations containing sucrose as a function of relative humidity and temperature during storage by TMDSC and ther-mogravimetric analysis. Craig et al. [1.163] found it helpful to asses the relaxation behavior of freeze-dried amorphous lactose by MTDSC. Relaxation times were calculated from measurements of Tg, and the magnitude of the relaxation endotherm. Scannnig was performed at 2°C/min with a modulation amplitude of 0.3 °C and a period of 60 s. 

The identification of phases in polymer blends can be accomplished in force modulation mode (FMM) AFM. Using FMM AFM the relative moduli (a convolution of storage and loss moduli) are mapped on the specimen surface. The rms amplitude of the FMM cantilever, driven in an oscillatory fashion, reflects directly the modulus of underlying polymer specimen. In the blend discussed below three phases can be differentiated. 

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