Stoichiometric Reactions of Carbenoids and Ylides

Stable carbenoids (carbene—metal complexes) have been readily available since Fischer s classical work. 

A key step in a synthesis of vitamin E [107] constitutes an illustration of the potentialities of these reagents in organic synthesis. 

A reactive titanium carbene intermediate is formed from a stable bridged titanium—aluminum methylene complex. 

Besides being active in cyclopropanation of olefins, this reagent is particularly useful to convert carbonyl groups to methylene compounds. 

The potentialities of this reagent are illustrated by the synthesis of C-glycosides and for example in a project directed toward the synthesis of citroviridin [108]. 

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Stoichiometric reactions of carbenoids and ylides(as carbenes precursors. 

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