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Stochastic Kinetic Analysis of a Single Receptor Molecule

2 Stochastic Kinetic Analysis of a Single Receptor Molecule [Pg.62]

Let us consider one single receptor molecule, which when bound and unbound by ligands X and F flips among states (0,0), (X, 0), (0, F), and (A , F). If nx and y are assumed constant, the master equation (actually the master-equation family) describing the dynamics of the probability distribution for this system is [Pg.63]

We also expect from the independency of both binding sites that the probabilities Pij (t) are given in terms of Px(t) and PyiO follows  [Pg.64]

Equations (6.9) and (6.10) are not new to us since we encountered them in Chap. 3. The readers are encouraged to demonstrate that their general solutions are  [Pg.64]




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