Stirred tank design impellers

A basic stirred tank design is shown in Fig. 23-30. Height to diameter ratio is H/D = 2 to 3. Heat transfer may be provided through a jacket or internal coils. Baffles prevent movement of the mass as a whole. A draft tube enhances vertical circulation. The vapor space is about 20 percent of the total volume. A hollow shaft and impeller increase gas circulation (as in Fig. 23-31). A splasher can be attached to the shaft at the hquid surface to improve entrainment of gas. A variety of impellers is in use. The pitched propeller moves the liquid axially, the flat blade moves it radially, and inclined blades move it both axially and radially. The anchor and some other designs are suited to viscous hquids. 

FIG. 23-30a A basic stirred tank design, not to scale, showing a lower radial impeller and an upper axial impeller boused in a draft tube. Four equally spaced baffles are standard. H = beigbt of liquid level, Dj = tank diameter, d = impeller diameter. For radial impellers, 0.3 < d/Dt < 0.6. 

FIG. 23-30 Basic stirred tank design and selected lands of impellers, (h) Propeller, (c) Turbine, (d) Hollow, (e) Anchor,... 

Figure 5-12. Typical proportion of stirred tank design with radial and axial impellers and baffles. The upper axial impeller is housed in a draft tube. For radial impellers,. 3 < d/Dt <. 6...

A further example for the design of a two-phase, multicompartment model for a stirred-tank double impeller system is illustrated in Figure 3.2 [6]. This model has been successfully applied to describe experimental observations of mixing in the gas and liquid phase. 

As will be shown later the equation above is identical to the mass balance equation for a continuous stirred-tank reactor. The recycle can be provided either by an external pump as shown in Fig. 5.4-18 or by an impeller installed within the reaction chamber. The latter design was proposed by Weychert and Trela (1968). A commercial and advantageously modified version of such a reactor has been developed by Berty (1974, 1979), see Fig. 5.4-19. In these reactors, the relative velocity between the catalyst particles and the fluid phases is incretised without increasing the overall feed and outlet flow rates. 

Figure 1.1 Design and development cycle for equipment-based design using pre-decided equipment, a mixing configuration is chosen by correlations and experience. For stirred tanks this configuration is given, e g., by the power-to-volume ratio P/V and the impeller diameter N. Then, CFD models are made to describe the flow field [1],...

Stirred-tank bioreactors are widely used in the modern biotechnological industry. Most products produced from animal cells on a large scale worldwide are manufactured in this type of bioreactor. In general, these reactors are very similar to fermenters used in industrial submerged culture of microorganisms, and are simple to design, having the shape of a tank and impellers to promote mixture of the contents. 

Until now, bioreactors of various types have been developed. These include loop-fluidized bed [14], spin filter, continuously stirred turbine, hollow fiber, stirred tank, airlift, rotating drum, and photo bioreactors [1]. Bioreactor modifications include the substitution of a marine impeller in place of a flat-bladed turbine, and the use of a single, large, flat paddle or blade, and a newly designed membrane stirrer for bubble-free aeration [13, 15-18]. Kim et al. [19] developed a hybrid reactor with a cell-lift impeller and a sintered stainless steel sparger for Thalictrum rugosum cell cultures, and cell densities of up to 31 g L1 were obtained by perfusion without any problems with mixing or loss of cell viability the specific berberine productivity was comparable to that in shake flasks. Su and Humphrey [20] conducted a perfusion cultivation in a stirred tank bio-... 

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